Consideration should be given to official guidance on the appropriate use of antibacterial agents. Therefore as the following situations may lead to an increased risk for ventricular arrhythmias (including torsades de pointes), clarithromycin should be used with caution in the following patients patients with coronary artery disease, severe cardiac insufficiency, conduction disturbances or clinically relevant bradycardia patients with electrolyte disturbances such as hypomagnesaemia. Coupon - biaxin 250mg tablet, noticescount 0, canonicallink httpswww.
Concomitant administration of clarithromycin and colchicine is contraindicated (see section 4. St johns wort) may induce the metabolism of clarithromycin. Long-term use may, as with other antibiotics, result in colonisation with increased numbers of non-susceptible bacteria and fungi.
It will not work for colds, flu, or other viral infections. Caution should also be exercised when administering clarithromycin to patients with moderate to severe renal impairment. Some patients may have had pre-existing hepatic disease or may have been taking other hepatotoxic medicinal products.
Caution is advised in patients with severe renal insufficiency (see section 4. In one study in 14 healthy volunteers, the concomitant administration of clarithromycin and terfenadine resulted in 2- to 3-fold increase in the serum level of the acid metabolite of terfenadine and in prolongation of the qt interval which did not lead to any clinically detectable effect. Careful monitoring of glucose is recommended (see section 4.
Concomitant administration of clarithromycin and oral midazolam is contraindicated (see section 4. . Therefore, it is important that sensitivity testing be performed.
Some observational studies have identified a rare short-term risk of arrhythmia, myocardial infraction and cardiovascular mortality associated with macrolides including clarithromycin. There was an error detecting your location, please manually enter your location below goodrx finds the lowest prices for prescriptions at pharmacies near you. Because of the large therapeutic window for clarithromycin, no dosage reduction should be necessary in patients with normal renal function. This information is for informational purposes only and is not meant to be a substitute for professional medical advice, diagnosis or treatment. Clarithromycin should be used with caution when administered concurrently with medications that induce the cytochrome cyp3a4 enzyme (see section 4.
Biaxin (clarithromycin) at more than 60,000 us pharmacies. Careful medical history is necessary since cdad has been reported to occur over two months after the administration of antibacterial agents. There have been post-marketing reports of colchicine toxicity with concomitant use of clarithromycin and colchicine, especially in the elderly, some of which occurred in patients with renal insufficiency. The prices we show are our best estimate while we believe our data to be generally accurate, we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. Clarithromycin has bactericidal activity against several bacterial strains.
Concomitant use of clarithromycin with lovastatin or simvastatin is contraindicated (see section 4. In tennessee, goodrx is registered as a prescription drug discount plan operator. Caution is advised regarding concomitant administration of clarithromycin and triazolobenzodiazepines, such as triazolam, and intravenous or oromucosal midazolam (see section 4. Therefore, discontinuation of clarithromycin therapy should be considered regardless of the indication. Clarithromycin is indicated in adults and children 12 years and older.
The concomitant use of clarithromycin and oral hypoglycaemic agents (such as sulphonylurias) andor insulin can result in significant hypoglycaemia. Consideration of these findings should be balanced with treatment benefits when prescribing clarithromycin. Concomitant administration of clarithromycin and oral midazolam is contraindicated (see section 4. Careful monitoring of glucose is recommended (see section 4. Macrolides have been reported to alter the metabolism of terfenadine resulting in increased levels of terfenadine which has occasionally been associated with cardiac arrhythmias, such as qt prolongation, ventricular tachycardia, ventricular fibrillation and torsades de pointes (see section 4. Goodrx provides no warranty for any of the pricing data or other information. In one study in 14 healthy volunteers, the concomitant administration of clarithromycin and terfenadine resulted in 2- to 3-fold increase in the serum level of the acid metabolite of terfenadine and in prolongation of the qt interval which did not lead to any clinically detectable effect. Furthermore, it might be necessary to monitor the plasma levels of the cyp3a inducer, which could be increased owing to the inhibition of cyp3a by clarithromycin (see also the relevant product information for the cyp3a4 inhibitor administered). Therefore, children under 12 years of age should use clarithromycin paediatric suspension (granules for oral suspension). Prolonged cardiac repolarisation and qt interval, imparting a risk of developing cardiac arrhythmia and torsades de pointes, have been seen in treatment with macrolides including clarithromycin (see section 4.The recommended adult dosage is 500 mg Biaxin Filmtab, 30 mg lansoprazole, and ... Patients with moderate renal impairment (CLcr of 30 to 60 mL/min) taking ...